NNTnet - EN

Number Needed to Treat for net effect (NNTnet): calculation and presentation¹

If for the treatment you consider,

the Number Needed to Treat for Benefit (NNTB) equals and

the Number Needed to Treat for Harm (NNTH) equals , then

the Number Needed to Treat for net effect (NNTnet) equals 0, which is the average number of patients who are needed to be treated to see the benefit exceeding the harm by one event.^2,3

Figure. The Number Needed to Treat for net effect (NNTnet)^2,3 for the treatment considered.

References

1. Coenen S, Colliers A. An online tool for the calculation and graphical presentation of the NNTnet. J Clin Epidemiol; in press. doi: 10.1016/j.jclinepi.2021.01.005

2. Coenen S, Colliers A. NNTnet combineert voor- en nadelen van behandeling. Huisarts Nu 2020;49:262.

3. Li G, Lip GYH, Marcucci M, et al. The number needed to treat for net effect (NNTnet) as a metric for measuring combined benefits and harms. J Clin Epidemiol 2020;125:100-7. doi: 10.1016/j.jclinepi.2020.05.031

Made available by Samuel Coenen and Bart Goethals (University of Antwerp)