Follow-up during pregnancy Afdrukken
do 02.10.2008
published in Huisarts Nu 2006; 35(5):261-98
  1. Routine antenatal care visits for low-risk pregnancy should be limited and targeted (level of evidence 1).
  2. Antenatal care starts preferably at 6-8 weeks with a thorough risk assessment (level of evidence 3).
  3. Antenatal screening for aneuploidia is presented to all pregnant women at the first consult, by means of informed consent (level of evidence 3).
  4. Routine detection of glycosuria and proteinuria by means of urine dipstick is not advisable (level of evidence 2)
    Urine culture at the beginning of the second trimester (weeks 12-16) suffices to screen for asymptomatic bacteriuria in pregnancy (level of evidence 2).
  5. At each prenatal consult, it is necessary to control blood pressure to screen for eclampsy (level of evidence 2).
  6. It is meaningful to screen all pregnant women between 24 and 28 weeks for gestational diabetes mellitus (level of evidence 2).
  7. At the time of the first blood sampling, it is strongly recommended to determine blood group, Rhesus factor and irregular antibodies (indirect coombs). These tests should be repeated at around 24 - 28 weeks. Pregnant women with negative Rhesus factor should routinely be administered preventive immunoglobulines at 28 weeks (level of evidence 2).
  8. At the time of the first blood sampling, the rubella- and toxoplasmosis titres should be determined. Preventive measures should be explained to non-immune pregnant woman. Cytomegalovirus and hepatitis C titre are not routinely assessed (level of evidence 2).
  9. Routine ultrasound during the first trimester (between 11-14 weeks of gestation) is important to determine the labour date, presence of multiple pregnancy and to screen for genetic deviations (level of evidence 3).
  10. Routine ultrasound during the first trimester (between 11-14 weeks of gestation) is important to determine the labour date, presence of multiple pregnancy and to screen for genetic deviations (level of evidence 3).
  11. In the second trimester of the pregnancy (between 20-22 weeks of gestation), ultrasound has a clear added value for the analysis of foetal structures and malformations (level of evidence 1).
  12. In normal pregnancies ultrasound in the third trimester (after 24 weeks) has restricted added value (level of evidence 1).
  13. Women should be offered screening for group B streptococcal infection (via rectovaginal culture) at 35 to 37 weeks' gestation (level of evidence 3).
Laatst aangepast: ma 06.10.2008