Prevention of neural tube defects Afdrukken
do 02.10.2008
published in Huisarts Nu 1998; 27 (9-10): 289-94

  • It is important that the GP explains a folate-rich diet to all pregnant women. Folic acid is found in raw vegetables, fruit, legumes and wholegrain products. However, this is insufficient. A supplement of 0.4 mg folic acid daily fromconception to the third month of pregnancy is necessary.
  • Intake of 4 mg folic acid for the same period is recommended for women in the risk groups. 
  •  Systematic detection of neural tube defects in all pregnant women by alphafetoprotein determination is not justifiable because of the high number of false-positive test results and the consequences this brings with it.
  • The GP can give the pregnant woman the necessary and understandable explanation on the value and consequences of an alphafetoprotein determination.
  • In the case of the high-risk groups, it is important to discuss the options for the test with the pregnant woman.
  • The possibility of supplementing the diet with folic acid can be considered by the government.
Laatst aangepast: ma 06.10.2008